Free nucleosome remodeling Image

nucleosome remodeling

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Marwan A.

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Image Generated: 16th February 2025

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Nucleosome Remodeling: DNA wrapped around histones (nucleosomes). SWI/SNF complex remodeling chromatin; HATs adding acetyl groups. Mutation labels: "SWI/SNF loss → condensed chromatin". Pre-Initiation Complex: TATA box with TFIID (TBP), TFIIH, RNAPII, and Mediator complex. Phosphorylation of RNAPII CTD. Aberrancy: "TBP mutation → no promoter binding". Initiation/Unwinding: TFIIH helicase (XPB/XPD) unwinding DNA helix. ATP molecules shown. Mutation: "XPB defect → impaired unwinding".

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nucleosome remodelingchromatin structuredna unwinding

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Biology

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FLUX 1.1 Pro

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